Active Probiotic Ingredients (API)

Probiotics Australia have a range of products that are commonly used as well as certain others that are supported by scientific research. These products are available for various market segments such as healthcare, functional foods, cosmetics as well as other novel applications. With evidence-based claims through trials or real word experience, you can choose the probiotic product that meets your particular needs!

 

Top Strains

Our key probiotics are products that have been well-studied and documented in scientific literature to confer empirical benefits and improve health. Our in-house quality-controlled genome sequencing steps ensures you receive a pure product.

 

Popular Probiotic Species

We also produce a range of probiotics that are ready to use in the functional food industry. Our commitment to quality ensures all products go through our high QA/QC standards. If you are part of the functional food industry you can leverage our products’ for key value in your range and confer a unique market advantage through Australian probiotics.

 

Strains available for contract manufacture

Our highly talented R & D team specializes in commercial scale-up of unique and natural strains of probiotics providing a unique capability that you can leverage for your next project. As an Australian Probiotics manufacturer following the TGA/cGMP standards, you can rest assured that your products would have gone through rigorous innovation and testing before reaching your end-user. Our current capabilities for scale-up production include, but not limited to, the list below.

Some of these products have been quite popular for us to include in our standard product offerings.

 

Next Generation Probiotics

 

Akkermansia

Akkermansia munciniphila is currently the sole member of a relatively new genus discovered about two decades ago. It is a gram-negative, fastidiously anaerobic bacteria which is non-spore forming. It has been recently investigated extensively for its association and prevention of obesity, diabetes, and inflammation. Briefly, individuals who have this organism present in their gut microbiome tend to be leaner. The microbe is also shown to have an inverse co-relation with several gut related conditions such as inflammatory bowel conditions.

Probiotics Australia: This is a next generation probiotic candidate and Probiotics Australia works towards various ways they can be promoted if already present in a person’s gut. While PA also works on commercializing the strain, there are certain regulations that need to be addressed with respect to next generation probiotics.

 

Faecalibacteria

Faecalibacterium prausnitzii is currently the only known species of this genus, which is seen to one of the more abundant microbes in the intestine. Research suggests that reduced levels of this microbe is linked with several diseases including obesity and mental health. As the microbe is quite fastidious in its requirements to be cultured in a laboratory setting, new and innovative steps are developed for creating this product.

Probiotics Australia: We constantly investigate developing new ways to promote or deliver such next generation microbes into the gut.

 

Pediococcus sp.

Part of the next generation probiotic strain(s), Pediococcus sp. (eg: Pediococcus pentosaceus) is a gram-positive LAB that is gaining interest as a functional food ingredient.

They are observed to improve taste and nutrition of food products, while their anti-microbial properties help in food preservation.

Pediococcus sp ferments food products to release certain organic compounds that help improve texture and taste profiles. While this is not unique to this probiotic, each probiotic used for fermentation can release its own unique set of organic compounds.

There are a few reports that highlight the genus’ probiotic capacity which include anti-inflammatory, antioxidant, and lipid-lowering abilities.

Probiotics Australia: We have actively worked upon the commercialization of P. acidilactici strain(s) which have evidence in aiding in several gut related conditions including IBS, IBD and bloating when used in combination with other probiotics. Some of these strains are in the pipeline for clinical trials for other disease conditions such a viral and upper respiratory tract infections.

 

Traditional Probiotics

 

Lactobacillus sp.

Lactobacillus is, or at least was, the largest genus within the group of lactic acid bacteria. In April 2020 an expert group published an update to the taxonomy or naming of these bacteria and many common “Lactobacilli” have been assigned a new name. Their functionality is unchanged and the new naming system allows scientists, consumers and the general public to more easily identify closely related probiotics. New genus names include Lacticaseibacillus, Ligilactobacillus and Limosilactobacillus

The “Lactobacilli” group plays an important role in human health, is the most common probiotic found in food, and it is diverse in its application to maintain human life and well-being.

Probiotics Australia: manufactures a wide range of Lactobacillus species as ones of its core offering, and they are a stocked products available at low MOQs. Certain products would be made to order with standard lead times and MOQs.

 

Bifidobacterium

Bifidobacterium are one of the major genera of probiotic bacteria that make up the gastrointestinal tract microbiota in mammals. They help the host perform essential functions such as digestion and staving off harmful bacteria.

Probiotics Australia: manufactures several key Bifidobacteria species as another core offering and are a stocked item available at low MOQs. Certain products would be made to order with standard lead times and MOQs.

 

Streptococcus.

Streptococcus is heterogeneous group of Gram-positive bacteria, has broad significance in medicine and industry. The probiotic species thermophilus is characterised by its rapid growth and active fermentation properties of milk which is one of two original strains used to make yogurt.

Probiotics Australia: manufactures S. thermophilus for pharmaceutical and functional food purposes.

 

Bacillus sp.

Bacillus is a gram-positive bacterial genus originally isolated from soil sources. Some of the species such as B. coagulans are used in the food industry due to their robustness via the processing steps and are shelf stable. They can help add CFU counts where the processing steps are likely to kill some of the other probiotics mentioned here. Bacillus has been given GRAS status (U.S FDA) and some studies shows benefits in gut health, diarrhea, constipation, and IBS.

Probiotics Australia: We have helped commercialize certain strains of pharmaceutical grade Bacillus sp. that goes into certain proprietary products, and can also supply food grade Bacillus sp.

 

Enterococcus sp.

The Enterococcus genus has the potential of being used as a probiotic, although several considerations are to be taken in strain selection.

They release certain enterocins that inhibit the growth of pathogens in the gut and due to this capacity to control bacteria that cause dysbiosis of the gut, they are sought after as a probiotic for microbiome regulation.

Similar to other probiotics, they help develop a positive organoleptic profile of the foods they are included into such as plant, meat and dairy-based products.

Enterococcus sp. is specially of interest in the veterinary applications and for use in farm animals (pigs and chickens) and pets (dogs and cats), while certain considerations are advised when incorporating this probiotic into your product. Discuss with our team for further information.

Probiotics Australia: currently offers this strain for animal products.

 

Saccharomyces sp.

The genus is quite popular as brewer’s yeast that is known to provide certain health benefits.

Saccharonyces is a popular strain used in baking and brewing processes; the strain is regularly used as starter cultures in the food industry.

More recently it is being investigated as a probiotic and included as a live or freeze-dried ingredient. The studies included this strain being used as a blend for reducing E. coli induced diarrhea (Bisson et. al, 2010), modulate the microbiome preserving intestinal diversity, modulate immunity and promote host-microbiome crosstalk.

Probiotics Australia: supplies shelf stable powder product of the strain that can be used in a variety of functional foods.